Magic Mushrooms (Psilocybe Cubensis)


God’s Flesh, Boomers, Simple Simon, Shrooms. There are a lot of nicknames for Psilocybin mushrooms, just as there are misconceptions. Psilocybin mushrooms have been used by indigenous and ancient civilizations for centuries, for spiritual and divine purposes, though in our modern times it is often demonized and classified as an illegal, dangerous drug. Despite the restriction and stigma placed upon it, it is still used worldwide by those seeking to strengthen their inherent spirituality, explore their nature and the nature of reality; and as well by those who just want to enjoy or experience a “trip”. Experiences with magic mushrooms are constantly labeled as being ‘life defining, life changing, mystical or spiritual’; It’s this nature of experience that draws in many seekers. The Psychonauts’ Guide is here to dispel all misconceptions, as well as to provide a detailed and practical guide to those whom are ready to explore the phenomena of altered states of consciousness.

Chemical Background

Psilocybin is a psychedelic compound found and produced in a wide variety of mushrooms, collectively known as ‘Magic Mushrooms’ or ‘Psilocybin Mushrooms’. It is a naturally occurring compound that induces a multitude of psychoactive and physiological effects on its consumer. After ingestion, psilocybin is converted to psilocin by the liver, which has mind-altering effects similar (but not identical) to other psychedelic compounds, such as LSD and DMT. These effects include, but are not limited to: an altered perception of time, distortion of space, increased parameters of thought, spiritual experiences, and euphoria. It is a tryptamine similar in structure to the neurotransmitter serotonin, which is responsible for the regulation of mood, appetite, and sleep. Psilocybin is registered as a Schedule I substance under the CSA (controlled substances act), classifying it as a highly dangerous and toxic substance, placing it alongside Heroin and above Cocaine, Amphetamine, Opium, and Methamphetamine in toxicity and potential for abuse; all this despite it being the least lethal and least dependent, ranking lower in dependency than Cannabis and alongside it, and LSD, in lethality.


Noted Effects

Effects vary by person, location,  state of mind. intention, company, and amount taken, but nonetheless are similar between consumers. Effects also vary by the potency of the mushrooms. The onset for effects is generally between 45 minutes to 2 hours, and has the potential to take much longer depending on potency, quantity, and whether or not the consumer has eaten anything prior. The duration of effects are usually  between 2-6 hours, and this, of course, also depends on potency and quantity. Before I present the common, consistent effects throughout various ‘levels’ of psilocybin consumption, I’d like to point out that there are common effects that may persist throughout all levels of dosage; There are also effects that you will feel  I’ll refer to these as ‘Omnidose effects’.

Omnidose effects

Regardless of how many grams of mushrooms you consume, there are certain effects that stay persistent throughout all levels. These effects can appear at any dosage, but are generally non-existent at lower doses and very strong on heavier doses. Effects such as:

  • A sedating, relaxing feeling, accompanied by drowsiness and excessive yawning
  • A warm, tingling, electric-like sensation
  • Feeling exceedingly light
  • Bouts of emotion that may seemingly appear out of nowhere, notably laughter and crying

Onset effects

These are effects that occur during the onset of psilocybin, before peaking. They may begin shortly after consumption, or any time afterwards, before reaching the peak of your trip.

  • A feeling of energy rising from your feet to your head, with effects becoming stronger as it rises (associated with the warm, tingling sensation aforementioned)
  • Shortness of breath
  • Chills or hot flashes


A micro-dose (.25-1 grams)


  • Clarity of vision
  • Everything and everybody appear to be more ‘present’
  • Lights are brighter and more colorful
  • Eyes feel relaxed


  • Sounds are clear and distinctive
  • Auditory hallucinations (of various internal/external experiences)
  • Tinnitus (constant buzzing, ringing, drumming in ear)


  • Feeling abundantly energetic
  • All senses are elevated, including intuitive and instinctive senses
  • Present and calm


Level 2

A mild dose (1-2.5 grams)




Level 3

A normal dose (2.5-3.5 grams)


Level 4

A strong dose (3.5-5 grams)




Level 5

A heroic dose (5 grams or more)





  • Clouds (and objects) may shift shapes and change color
  • Splitting/chopping of images
Historic Background

Medicinal Use & Micro-dosing

Despite it’s illegality, magic mushrooms remain as one of the most beneficial medicines available to all mankind. Its mental and spiritual effects are profound in alleviating/curing many mental, emotional, and even physical afflictions. It’s been widely stated (after countless research) as being extremely beneficial in eliminating depression and suppressing emotional, mental, and physical pain associated with cancer. Aside from cancer, it has been shown to help those with a deadly illness better deal with their feelings of hopelessness and their imminent death. Another notable benefit is its aid in eliminating addictive tendencies in substance abuse.

Also, regardless of whether the individual is religious or not, Psilocybin is an advocate to the human spirit and allows one to become better in touch with one’s existence, spirituality, and nature, as discussed below.

Entheogenic use

Like most psychedelics, Psilocybin can be, and is used entheogenically (spiritually). Given it’s psychoactive effects, natives have used it for thousands of years to connect to nature, the spirit, and the universe. There are depictions of psilocybin mushroom use in cave art that pre-dates recorded history


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